Consuming Too Much Sugar? You May Develop This Liver Disease
Updated : June 17, 2021 10:06 IST
Excessive sugar consumption is debilitating for your overall health. Here is what can happen to your liver if you keep having too much of this high-calorie containing food item.
Do you have a sweet tooth and you constantly keep craving sugar? If yes, you are at a high risk of developing fatty liver disease. This is what a recent research at the IIT Mandi has revealed. According to scientists, there is a biochemical relationship between too much sugar consumption and the onset of fatty liver disease which is also known as hepatic steatosis. It occurs when fat builds up in your liver. This can cause inflammation in the organ and that can further damage it by creating scarring. This can lead to liver failure in severe cases. The liver keeps your body clean by filtering harmful substances from your blood.
Role of Excessive Sugar Consumption in Fatty Liver Disease
Your liver converts excessive sugar and carbohydrates into fat during the hepatic De Novo Lipogenesis or DNL process. This causes the accumulation of fat in the liver. According to the study published in the Journal of Biological Chemistry, “the sugar-mediated shuttling of hepatic NF-KB p65 reduces the levels of another protein, sorcin, which in turn activates liver DNL through a cascading biochemical pathway.” The study has revealed that a decrease in the level of sorcin reduces NF-KB inhibitor’s ability to lower the level of lipid.
Apart from too much sugar consumption, factors including obesity, insulin resistance, high blood glucose level, etc. also contribute to the onset of fatty liver disease. It is characterized by fatigue, loss of appetite, itchy skin, yellow skin, and eyes, etc.
Now, you know what you must not do in order to keep fatty liver disease at bay.